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David De Franco, DMD, MSD

Private Practice:

Galleria Passarella, 2 - 20121 Milano

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Received his B.A. degree in Biochemistry at the University of Pennsylvania.

Received his D.M.D. degree in Dentistry at the University of Connecticut.

Received his D.M.Sc. degree in Oral Biology from Harvard University and the Master’s degree in Orthodontics at Harvard School of Dental Medicine and Forsyth Dental Center.

Assistant Professor in Orthodontics at the University of Louisville School of Dentistry.

Associate Professor of Orthodontics at Harvard School of Dental Medicine and Children’s Hospital, Boston.

Received his Master’s degree in Orthodontics at the University of San Raffaele Hospital in Milan.

Diplomate of the American Board of Orthodontics

Diplomate of the European Board of Orthodontics

Diplomate of the Italian Board of Orthodontics.

He is a member of numerous associations (American Association of Orthodontics, Eastern Component Edward H. Angle Society, European Orthodontic Society, Italian Society of Orthodontics, Italian Association of Specialists in Orthodontics and Italian Academy of Orthodontics).
He practices orthodontics in Milan.



  • Demoli U, Toffenetti A., De Franco DJ. Estetica in zirconio: lo stato dell’arte pazienti adolescenti. Dental Dialogue 2007; 14:58-65
  • De Franco DJ. Matrix Gla protein gene expression in rat mandibular condyle during development and under compressive forces. Angle East 2004;5 : 9-10.
  • De Franco DJ. Analisi tridimensionale della crescita mandibolare [Thesis]. Milan, Italy: University of Milan, 1998. Ferrario VF, Sforza C, De Franco DJ. Mandibular shape and skeletal divergency. European Journal of Orthodontics 1999;21:145-153.
  • Calvani M, Alessandri C, Paolone G, Rosengart L, Di Caro A, De Franco D.J. Correlation between Epstein Barr virus antibodies, serum IgE and atopic desease. Pediatric Allergy and Immunology 1997; 8:91-96.
  • De Franco D. J., Colucci S, Grano M, Zambonin Zallone A. Effect of retinol and osteoclast media on rat periosteal osteoblasts. Europ J Orthod 1996; 18: 409-410.
  • Ferrario VF, Sforza C, Dalloca LL, De Franco D.J. Assessment of facial form modifications in orthodontics. Proposal of a modified computerized mesh diagram analysis. American Journal of Orthodontics and Dentofacial Orthopedics 1996; 109: 263:270.
  • De Franco D.J., Spiller RE, von Fraunhofer JA. Frictional resistances using Teflon-coated ligatures with various bracket-archwire combinations. Angle Orthodontist 1995; 65:63-72.
  • De Franco D.J., Sforza C, Ferrario FF. Facial form assessment using a computerized modified mesh diagram analysis. Europ J Orthod 1994; 16:444.
  • De Franco D.J., Chung KS, Gerstenfeld LC, Nishimura I. Type X collagen gene expression in rat mandibular condyle. J Dental Res 1993; 72:252.
  • De Franco D.J., Lian JB, Glowacki J. Differential effects of glucocorticoids on recruitment and activity of osteoclasts induced by normal and osteocalcin deficient bone implanted in rats. Endocrinology 1992; 131:114-121.
  • De Franco D.J., Gerstenfeld LC. Biomechanical effects of compressive forces on rat mandibular condyle in vitro. Europ J Orthod 1992; 14: 397.
  • De Franco D.J., Glowacki J, Cox KA, Lian JB. Normal bone particles are preferentially resorbed in the presence of osteocalcin-deficient bone particles in vivo. Calcified Tissue International 1991; 49:46-54.
  • De Franco D.J., Gerstenfeld LC. Skeletal tissue gene expression during craniofacial development. J Dental Res 1991; 70:271.
  • De Franco DJ, New CG, Gorr S-U, Fasciotto BH, Cohn DV. (1990) Evidence for pancreastatin synthesis in pig parathyroid. J Dental Res 69:294.Spiller RE,
  • De Franco DJ, Story RJ, von Fraunhofer JA. (1990) Friction forces in bracket-wire-ligature combinations. J Dental Res 69:155.
  • Fasciotto BH, Gorr S-U, De Franco DJ, Levine MA, Cohn DV. (1989) Pancreastatin, a presumed product of chromogranin A (sectretory protein-I) processing, inhibits secretion from porcine parathyroid cells in culture. Endocrinology 125:1617-1622.
  • Fasciotto BH, Gorr S-U, De Franco D.J., Levine MA, Cohn DV. Is pancreastatin an autocrine inhibitor of parathyroid secretion? J Bone Min Res 1989; 4:S267.
  • De Franco D.J., Lian J.B. Effects of 1,25 (OH)2 D3 on resorption of normal and osteocalcin-depleted bone. J Dental Res 1989; 68:257.
  • De Franco D.J., Glowacki J., Lian J.B. The recruitment and differentiation of bone-resorbing cells by normal and osteocalcin-deficient bone particles. Calcif Tis Int 1988;42:A29.
  • De Franco D.J., Lian J.B., Glowacki J. Hydrocortisone effects on resorption of normal and osteocalcin deficient bone. J Dental Res 1988;67:349.
  • De Franco D.J. The role of osteocalcin in bone resorption and the effects of hydrocortisone and vitamin D on bone resorptionin the rat [Thesis]. Boston, Massachusetts: Harvard School of Dental Medicine, 1988.